Pathway engineering and organism development for ethanol production from cellulosic biomass using thermophilic bacteria
Conference
·
OSTI ID:127025
- Dartmouth College, Hanover, NH (United States); and others
Thermophilic bacteria collectively exemplify organisms that produce both cellulose and ethanol while fermenting both the cellulose and hemicellulose components of biomass. As a result, thermophiles could be the basis for highly streamlined and cost-effective processes for production of renewable fuels and chemicals. Recent research results involving ethanol production from thermophilic bacteria will be presented, with a primary focus on work pursuant to molecularly-based pathway engineering to increase ethanol selectivity. Specifically, we will describe the restriction endonuclease systems operative in Clostridium thermocellum and C. thermosaccharolyticum, as well as efforts to document and improve transformation of these organisms and to clone key catabolic enzymes. In addition, selected results from fermentation studies will be presented as necessary in order to present a perspective on the status of thermophilic ethanol production.
- OSTI ID:
- 127025
- Report Number(s):
- CONF-950402--
- Country of Publication:
- United States
- Language:
- English
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