Application of an Informatics-Based Decision-Making Framework and Process to the Assessment of Radiation Safety in Nanotechnology

Hoover, Mark D.; Myers, David S.; Cash, Leigh J.; Guilmette, Raymond A.; Kreyling, Wolfgang G.; Oberdörster, Günter; Smith, Rachel; Cassata, James R.; Boecker, Bruce B.; Grissom, Michael P.

doi:10.1097/HP.0000000000000250

Application of an Informatics-Based Decision-Making Framework and Process to the Assessment of Radiation Safety in Nanotechnology

Journal Article · Thu Jan 01 00:00:00 EST 2015 · Health Physics

DOI:https://doi.org/10.1097/HP.0000000000000250· OSTI ID:1239283

Hoover, Mark D. ^[1]; Myers, David S. ^[2]; Cash, Leigh J. ^[1]; Guilmette, Raymond A. ^[3]; Kreyling, Wolfgang G. ^[4]; Oberdörster, Günter ^[5]; Smith, Rachel ^[6]; Cassata, James R. ^[7]; Boecker, Bruce B. ^[8]; Grissom, Michael P. ^[9]

Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Livermore, CA (United States)
Ray Guilmette & Associates, LLC, Perry, ME (United States)
Helmholtz Zentrum MÃ¼nchen (Germany)
Univ. of Rochester, NY (United States)
Public Health England (United Kingdom)
National Council on Radiation Protection and Measurements, Bethesda, MD (United States)
Lovelace Respiratory Research Inst., Albuquerque, NM (United States)
MPG-HP, Inc., Riverside, CA (United States)

The National Council on Radiation Protection and Measurements (NCRP) has established NCRP Scientific Committee 2-6 to develop a report on the current state of knowledge and guidance for radiation safety programs involved with nanotechnology. Nanotechnology is the understanding and control of matter at the nanoscale, at dimensions between approximately 1 and 100 nanometers, where unique phenomena enable novel applications. While the full report is in preparation, this article presents and applies an informatics-based decision-making framework and process through which the radiation protection community can anticipate that nano-enabled applications, processes, nanomaterials, and nanoparticles are likely to become present or are already present in radiation-related activities; recognize specific situations where environmental and worker safety, health, well-being, and productivity may be affected by nano-related activities; evaluate how radiation protection practices may need to be altered to improve protection; control information, interpretations, assumptions, and conclusions to implement scientifically sound decisions and actions; and confirm that desired protection outcomes have been achieved. This generally applicable framework and supporting process can be continuously applied to achieve health and safety at the convergence of nanotechnology and radiation-related activities.

Research Organization:: Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)

Sponsoring Organization:: USDOE

Grant/Contract Number:: AC52-06NA25396

OSTI ID:: 1239283

Report Number(s):: LA--UR-14-28101

Journal Information:: Health Physics, Journal Name: Health Physics Journal Issue: 2 Vol. 108; ISSN 0017-9078

Publisher:: Health Physics SocietyCopyright Statement

Country of Publication:: United States

Language:: English

References (14)

Experimental study of nanoparticles penetration through commercial filter media Kim, Seong Chan; Harrington, Matthew S.; Pui, David Y. H. Journal of Nanoparticle Research, Vol. 9, Issue 1 https://doi.org/10.1007/s11051-006-9176-4	journal	October 2006
The evolution of risk perceptions Kahan, Dan M. Nature Nanotechnology, Vol. 4, Issue 11 https://doi.org/10.1038/nnano.2009.329	journal	November 2009
Bombesin functionalized gold nanoparticles show in vitro and in vivo cancer receptor specificity Chanda, N.; Kattumuri, V.; Shukla, R. Proceedings of the National Academy of Sciences, Vol. 107, Issue 19 https://doi.org/10.1073/pnas.1002143107	journal	April 2010
Factors Affecting the Mobility of Plutonium-238 Dioxide in the Rat Stradling, G. N.; Ham, G. J.; Smith, H. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, Vol. 34, Issue 1 https://doi.org/10.1080/09553007814550611	journal	January 1978
Filtration Performance of NIOSH-Approved N95 and P100 Filtering Facepiece Respirators Against 4 to 30 Nanometer-Size Nanoparticles Rengasamy, Samy; King, William P.; Eimer, Benjamin C. Journal of Occupational and Environmental Hygiene, Vol. 5, Issue 9 https://doi.org/10.1080/15459620802275387	journal	July 2008
Nanoparticle Filtration Performance of Filtering Facepiece Respirators and Canister/cartridge Filters Rengasamy, Samy; BerryAnn, Roland; Szalajda, Jonathan Journal of Occupational and Environmental Hygiene, Vol. 10, Issue 9 https://doi.org/10.1080/15459624.2013.818229	journal	September 2013
The in Vivo Solubility of Plutonium-239 Dioxide in the Rat Lung Smith, H.; Stradling, G. N.; Loveless, B. W. Health Physics, Vol. 33, Issue 6 https://doi.org/10.1097/00004032-197712000-00004	journal	January 1977
Ultrafine 239PuO2 Aerosol Generation, Characterization and Short-term Inhalation Study in the Rat Kanapilly, G. M.; Diel, J. H. Health Physics, Vol. 39, Issue 3 https://doi.org/10.1097/00004032-198009000-00009	journal	January 1980
Implications of Radiation Dose and Exposed Populations on Radiation Protection in the 21st Century Boice, John D. Health Physics, Vol. 106, Issue 2 https://doi.org/10.1097/HP.0000000000000024	journal	January 2014
Communication of Radiation Benefits and Risks in Decision Making: some Lessons Learned Locke, Paul A. Health Physics, Vol. 101, Issue 5 https://doi.org/10.1097/HP.0b013e3182299539	journal	January 2011
Cyclotron Production of Radioactive ${\hbox{CeO}} _{2}$ Nanoparticles and Their Application for In Vitro Uptake Studies Simonelli, F.; Marmorato, P.; Abbas, K. IEEE Transactions on NanoBioscience, Vol. 10, Issue 1 https://doi.org/10.1109/TNB.2011.2119491	journal	March 2011
Nanotechnology for the biologist McNeil, Scott E. Journal of Leukocyte Biology, Vol. 78, Issue 3 https://doi.org/10.1189/jlb.0205074	journal	May 2005
Effects of Particle Size and Morphology on Filtration of Airborne Nanoparticles Wang, Jing KONA Powder and Particle Journal, Vol. 30, Issue 0 https://doi.org/10.14356/kona.2013024	journal	January 2013
Forecasting Nano Law: Defining Nano Feitshans, Ilise L. Nanotechnology Perceptions, Vol. 8, Issue 1 https://doi.org/10.4024/N15FE11A.ntp.08.01	journal	March 2012

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ICRP Publication 141: Occupational Intakes of Radionuclides: Part 4 Paquet, F.; Bailey, M. R.; Leggett, R. W. Annals of the ICRP, Vol. 48, Issue 2-3 https://doi.org/10.1177/0146645319834139	journal	December 2019
The Nanomaterial Data Curation Initiative: A collaborative approach to assessing, evaluating, and advancing the state of the field Hendren, Christine Ogilvie; Powers, Christina M.; Hoover, Mark D. Beilstein Journal of Nanotechnology, Vol. 6 https://doi.org/10.3762/bjnano.6.179	journal	January 2015

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Application of an Informatics-Based Decision-Making Framework and Process to the Assessment of Radiation Safety in Nanotechnology

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