Ketol-acid reductoisomerase enzymes and methods of use

Govindarajan, Sridhar; Li, Yougen; Liao, Der-Ing; O'Keefe, Daniel P.; Minshull, Jeremy Stephen; Rothman, Steven Cary; Tobias, Alexander Vincent

Ketol-acid reductoisomerase enzymes and methods of use

Patent · Tue Oct 27 04:00:00 EDT 2015

OSTI ID:1224448

Govindarajan, Sridhar; Li, Yougen; Liao, Der-Ing; O'Keefe, Daniel P.; Minshull, Jeremy Stephen; Rothman, Steven Cary; Tobias, Alexander Vincent

Provided herein are polypeptides having ketol-aid reductoisomerase activity as well as microbial host cells comprising such polypeptides. Polypeptides provided herein may be used in biosynthetic pathways, including, but not limited to, isobutanol biosynthetic pathways.

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Research Organization:: Butamax Advanced Biofuels LLC, Wilmington, DE (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AR0000006

Assignee:: Butamax Advanced Biofuels LLC (Wilmington, DE)

Patent Number(s):: 9,169,467

Application Number:: 13/891,963

OSTI ID:: 1224448

Country of Publication:: United States

Language:: English

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