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Title: Polypeptide having beta-glucosidase activity and uses thereof

Patent ·
OSTI ID:1213473

The invention relates to a polypeptide comprising the amino acid sequence set out in SEQ ID NO: 2 or an amino acid sequence encoded by the nucleotide sequence of SEQ ID NO: 1, or a variant polypeptide or variant polynucleotide thereof, wherein the variant polypeptide has at least 70% sequence identity with the sequence set out in SEQ ID NO: 2 or the variant polynucleotide encodes a polypeptide that has at least 70% sequence identity with the sequence set out in SEQ ID NO: 2. The invention features the full length coding sequence of the novel gene as well as the amino acid sequence of the full-length functional polypeptide and functional equivalents of the gene or the amino acid sequence. The invention also relates to methods for using the polypeptide in industrial processes. Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins.

Research Organization:
DSM IP Assets B.V., Heerlen (Netherlands)
Sponsoring Organization:
USDOE
DOE Contract Number:
FC36-08GO18079
Assignee:
DSM IP Assets B.V. (Heerlen, NL)
Patent Number(s):
9,121,013
Application Number:
13/806,124
OSTI ID:
1213473
Resource Relation:
Patent File Date: 2011 Jun 23
Country of Publication:
United States
Language:
English

References (4)

Recombinant β-glucosidase variants for production of soluble sugars from cellulosic biomass patent March 2012
Expression in Trichoderma reesei and characterisation of a thermostable family 3 β-glucosidase from the moderately thermophilic fungus Talaromyces emersonii journal December 2004
A thermotolerant β-glucosidase isolated from an endophytic fungi, Periconia sp., with a possible use for biomass conversion to sugars journal October 2009
Cloning and sequencing of the cDNA encoding β-glucosidase 1 from Aspergillus aculeatus journal September 1996