Relationship between linear energy transfer and behavioral toxicity in rats following exposure to protons and heavy particles. (Reannouncement with new availability information)
Technical Report
·
OSTI ID:118014
Rats were exposed to protons (155 MeV) or to helium (165 MeV/amu), neon (522 MeV/amu) or argon (670 MeV/amu) particles to evaluate the behavioral toxicity of these types of radiations. Behavioral toxicity was assessed using the conditioned taste aversion paradigm. Exposure to all types of radiation produced dose-dependent increases in the intensity of the acquired taste aversion. However, the intensity of the aversions, measured as the dose that produced a 50% decrease in the intake of the sucrose-conditioned stimulus, did not show significant variation as a function of the linear energy transfer (LET) of the radiation. The results are discussed in terms of the relationship between LET and behavioral toxicity.
- Research Organization:
- Armed Forces Radiobiology Research Inst., Bethesda, MD (United States)
- OSTI ID:
- 118014
- Report Number(s):
- AD-A--245531/9/XAB; AFRRI-SR--91-52
- Country of Publication:
- United States
- Language:
- English
Similar Records
Assessment of the behavioral toxicity of high-energy iron particles compared to other qualities of radiation
An assessment of the behavioral toxicity of high-energy iron particles compared to other qualities of radiation
Attenuation and cross-attenuation in taste-aversion learning in the rat: Studies with ionizing radiation, lithium chloride, and ethanol. Scientific report
Technical Report
·
Sat Dec 31 23:00:00 EST 1988
·
OSTI ID:7164853
An assessment of the behavioral toxicity of high-energy iron particles compared to other qualities of radiation
Journal Article
·
Sat Jul 01 00:00:00 EDT 1989
· Radiation Research; (USA)
·
OSTI ID:5669064
Attenuation and cross-attenuation in taste-aversion learning in the rat: Studies with ionizing radiation, lithium chloride, and ethanol. Scientific report
Technical Report
·
Sat Dec 31 23:00:00 EST 1988
·
OSTI ID:5857530