Anti-cancer agents based on 6-trifluoromethoxybenzimidazole derivatives and method of making
Patent
·
OSTI ID:1176474
The present disclosure relates to novel compounds having the structural Formulas (1a,1b), stereoisomers, tautomers, racemics, prodrugs, metabolites thereof, or pharmaceutically acceptable salt and/or solvate thereof as chemotherapy agents for treating of cancer, particularly androgen-independent prostate cancer. The disclosure also relates to methods for preparing said compounds, and to pharmaceutical compositions comprising said compounds.
- Research Organization:
- U.S. Dept. of Energy, Washington, D.C. (United States)
- Sponsoring Organization:
- USDOE
- Assignee:
- The United States of America as represented by the United States Department of Energy (Washington, DC)
- Patent Number(s):
- 8,242,284
- Application Number:
- 12/862,168
- OSTI ID:
- 1176474
- Country of Publication:
- United States
- Language:
- English
Synthesis of benzamide derivatives as TRPV1 antagonists
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