Compositions and methods comprising cellulase variants with reduced affinity to non-cellulosic materials

Cascao-Pereira, Luis G.; Kaper, Thijs; Kelemen, Bradley R.; Liu, Amy D.

Title: Compositions and methods comprising cellulase variants with reduced affinity to non-cellulosic materials

Patent · Tue Aug 07 00:00:00 EDT 2012

OSTI ID:1176468

Cascao-Pereira, Luis G.; Kaper, Thijs; Kelemen, Bradley R.; Liu, Amy D.

The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions.

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Research Organization:: Danisco US Inc., Palo Alto, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: FC36-08GO18078

Assignee:: Danisco US Inc. (Palo Alto, CA)

Patent Number(s):: 8,236,542

Application Number:: 12/477,887

OSTI ID:: 1176468

Resource Relation:: Patent File Date: 2009 Jun 03

Country of Publication:: United States

Language:: English

References (15)

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Crystal structure of a bacterial family-III cellulose-binding domain: a general mechanism for attachment to cellulose. Tormo, J.; Lamed, R.; Chirino, A. J. The EMBO Journal, Vol. 15, Issue 21, p. 5739-5751 https://doi.org/10.1002/j.1460-2075.1996.tb00960.x	journal	November 1996
Molecular Cloning of Exo–Cellobiohydrolase I Derived from Trichoderma Reesei Strain L27 Shoemaker, S.; Schweickart, V.; Ladner, M. Nature Biotechnology, Vol. 1, Issue 8, p. 691-696 https://doi.org/10.1038/nbt1083-691	journal	October 1983
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