Synthesis of 3'-, or 5'-, or internal methacrylamido-modified oligonucleotides
Patent
·
OSTI ID:1176258
New modifiers were synthesized for incorporation of a methacrylic function in 3'-, 5'- and internal positions of oligonucleotides during solid phase synthesis. A modifier was used for synthesis of 5'-methacrylated oligonucleotides for preparation of microarrays by a co-polymerization method.
- Research Organization:
- Argonne National Laboratory (ANL), Argonne, IL (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- W-31-109-ENG-38
- Assignee:
- UChicago Argonne, LLC (Chicago, IL)
- Patent Number(s):
- 7,705,136
- Application Number:
- 11/066,791
- OSTI ID:
- 1176258
- Country of Publication:
- United States
- Language:
- English
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