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Biosensor compositions and methods of use

Patent ·
OSTI ID:1175421
; ;
Provided are pore-subunit polypeptides covalently linked to one or more sensing moieties, and uses of these modified polypeptides to detect and/or measure analytes or physical characteristics within a given sample.
Research Organization:
Texas A And M University, College Station, TX (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG03-97ER20271
Assignee:
Texas A And M University (College Station, TX)
Patent Number(s):
6,916,665
Application Number:
09/781,697
OSTI ID:
1175421
Country of Publication:
United States
Language:
English

References (7)

A Protein Pore with a Single Polymer Chain Tethered within the Lumen journal March 2000
Sensing proteins outside of the box journal October 2000
The Gramicidin-Based Biosensor: A Functioning Nano-Machine
  • Cornell, B. A.; Braach-Maksvytis, V. L. B.; King, L. G.
  • Novartis Foundation Symposium 225 ‐ Gramicidin and Related Ion Channel‐Forming Peptides: Gramicidin and Related Ion Channel‐Forming Peptides: Novartis Foundation Symposium 225 https://doi.org/10.1002/9780470515716.ch15
book September 2007
Designed protein pores as components for biosensors journal July 1997
Designed membrane channels and pores journal February 1999
Detecting protein analytes that modulate transmembrane movement of a polymer chain within a single protein pore journal October 2000
Calixarenes, Macrocycles with (Almost) Unlimited Possibilities journal April 1995

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