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Title: Biosensor compositions and methods of use

Abstract

Provided are pore-subunit polypeptides covalently linked to one or more sensing moieties, and uses of these modified polypeptides to detect and/or measure analytes or physical characteristics within a given sample.

Inventors:
; ;
Publication Date:
Research Org.:
Texas A And M University, College Station, TX (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1175421
Patent Number(s):
6,916,665
Application Number:
09/781,697
Assignee:
Texas A And M University (College Station, TX)
DOE Contract Number:  
FG0397ER20271
Resource Type:
Patent
Country of Publication:
United States
Language:
English

Citation Formats

Bayley, Hagan P., Howorka, Stefan G., and Movileanu, Liviu. Biosensor compositions and methods of use. United States: N. p., 2005. Web.
Bayley, Hagan P., Howorka, Stefan G., & Movileanu, Liviu. Biosensor compositions and methods of use. United States.
Bayley, Hagan P., Howorka, Stefan G., and Movileanu, Liviu. 2005. "Biosensor compositions and methods of use". United States. https://www.osti.gov/servlets/purl/1175421.
@article{osti_1175421,
title = {Biosensor compositions and methods of use},
author = {Bayley, Hagan P. and Howorka, Stefan G. and Movileanu, Liviu},
abstractNote = {Provided are pore-subunit polypeptides covalently linked to one or more sensing moieties, and uses of these modified polypeptides to detect and/or measure analytes or physical characteristics within a given sample.},
doi = {},
url = {https://www.osti.gov/biblio/1175421}, journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jul 12 00:00:00 EDT 2005},
month = {Tue Jul 12 00:00:00 EDT 2005}
}

Works referenced in this record:

Sensing proteins outside of the box
journal, October 2000


A Protein Pore with a Single Polymer Chain Tethered within the Lumen
journal, March 2000


Calixarenes, Macrocycles with (Almost) Unlimited Possibilities
journal, April 1995


Detecting protein analytes that modulate transmembrane movement of a polymer chain within a single protein pore
journal, October 2000


The Gramicidin-Based Biosensor: A Functioning Nano-Machine
book, September 2007

  • Cornell, B. A.; Braach-Maksvytis, V. L. B.; King, L. G.
  • Novartis Foundation Symposium 225 ‐ Gramicidin and Related Ion Channel‐Forming Peptides: Gramicidin and Related Ion Channel‐Forming Peptides: Novartis Foundation Symposium 225
  • https://doi.org/10.1002/9780470515716.ch15