Pnp gene modification for improved xylose utilization in Zymomonas

Caimi, Perry G G; Qi, Min; Tao, Luan; Viitanen, Paul V; Yang, Jianjun

Pnp gene modification for improved xylose utilization in Zymomonas

Patent · Tue Dec 16 04:00:00 EST 2014

OSTI ID:1165440

Caimi, Perry G G; Qi, Min; Tao, Luan; Viitanen, Paul V; Yang, Jianjun

The endogenous pnp gene encoding polynucleotide phosphorylase in the Zymomonas genome was identified as a target for modification to provide improved xylose utilizing cells for ethanol production. The cells are in addition genetically modified to have increased expression of ribose-5-phosphate isomerase (RPI) activity, as compared to cells without this genetic modification, and are not limited in xylose isomerase activity in the absence of the pnp modification.

Research Organization:: E I Du Pont de Nemours and Company, Wilmington, DE (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: FC36-07GO17056

Assignee:: E I Du Pont de Nemours and Company (Wilmington, DE)

Patent Number(s):: 8,911,983

Application Number:: 13/711,646

OSTI ID:: 1165440

Country of Publication:: United States

Language:: English

References (12)

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