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Zymomonas with improved xylose utilization

Patent ·
OSTI ID:1025535
 [1];  [2];  [3];  [4];  [5];  [6];  [7];  [7];  [8]
  1. West Chester, PA
  2. Havertown, PA
  3. New Hope, PA
  4. Kennett Square, PA
  5. Wilmington, DE
  6. East Fallowfield, PA
  7. Lakewood, CO
  8. Centennial, CO
+ Show Author Affiliations
Strains of Zymomonas were engineered by introducing a chimeric xylose isomerase gene that contains a mutant promoter of the Z. mobilis glyceraldehyde-3-phosphate dehydrogenase gene. The promoter directs increased expression of xylose isomerase, and when the strain is in addition engineered for expression of xylulokinase, transaldolase and transketolase, improved utilization of xylose is obtained.
Research Organization:
E. I. du Pont de Nemours and Company (Wilmington, DE)
Sponsoring Organization:
USDOE
DOE Contract Number:
FC36-03GO13146
Assignee:
E. I. du Pont de Nemours and Company (Wilmington, DE); Alliance for Sustainable Energy LLC (Wilmington, DE)
Patent Number(s):
7,998,722
Application Number:
12/410,501
OSTI ID:
1025535
Country of Publication:
United States
Language:
English

References (24)

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