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Title: Protection against herbivores

Patent ·
OSTI ID:1162110

The present invention relates to genes, proteins and methods comprising molecules that alter amino acid levels. In one embodiment, the present invention relates to altering guanidino substrate hydrolysis activities in plants, arthropods and microorganisms using molecules within the arginase family and other molecules that alter an amino acid levels. In ones embodiment, the present invention relates to altering threonine substrate deamination and dehydration activities in plants, arthropods and microorganisms using molecules within the threonine deaminase family and other molecules that alter amino acid levels. In one embodiment, the present invention relates to using genes, proteins and methods comprising arginase or threonine deaminase for altering the pathophysiology of plants, arthropods and microorganisms. In a preferred embodiment, the present invention relates to altering guanidino substrate hydrolysis activity in plants, arthropods, and microorganisms using arginase. In another preferred embodiment, the invention relates to altering threonine substrated deamination and dehydration activity in plants, arthropods, and microorganisms using threonine deaminase. In some embodiments, the invention related to overexpression and increased activity of arginase, threonine deaminase and a proteinase inhibitor.

Research Organization:
Michigan State Univ., East Lansing, MI (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-91ER20021
Assignee:
Board of Trustees of Michigan State University (East Lansing, MI)
Patent Number(s):
8,871,999
Application Number:
11/666,714
OSTI ID:
1162110
Resource Relation:
Patent File Date: 2005 Oct 31
Country of Publication:
United States
Language:
English

References (6)

Expressed sequences of arabidopsis thaliana patent-application June 2003
Polynucleotides and polypeptides, materials incorporating them and methods for using them patent-application July 2003
Methods for stimulating nervous system regeneration and repair by regulating arginase I and polyamine synthesis patent-application November 2003
Regulation of Plant Arginase by Wounding, Jasmonate, and the Phytotoxin Coronatine journal August 2004
Nucleotide Sequence of Arabidopsis thaliana Arginase Expressed in Yeast journal April 1995
Regulation of loblolly pine (Pinus taeda L.) arginase in developing seedling tissue during germination and post-germinative growth journal January 2001

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