Systems and methods for laser assisted sample transfer to solution for chemical analysis
Patent
·
OSTI ID:1134059
Systems and methods are described for laser ablation of an analyte from a specimen and capturing of the analyte in a dispensed solvent to form a testing solution. A solvent dispensing and extraction system can form a liquid microjunction with the specimen. The solvent dispensing and extraction system can include a surface sampling probe. The laser beam can be directed through the surface sampling probe. The surface sampling probe can also serve as an atomic force microscopy probe. The surface sampling probe can form a seal with the specimen. The testing solution including the analyte can then be analyzed using an analytical instrument or undergo further processing.
- Research Organization:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Organization:
- USDOE
- Assignee:
- UT-Battelle, LLC (Oak Ridge, TN); University of Tennessee Research Foundation (Knoxville, TN)
- Patent Number(s):
- 8,742,338
- Application Number:
- 13/949,777
- OSTI ID:
- 1134059
- Country of Publication:
- United States
- Language:
- English
Nanodispenser for attoliter volume deposition using atomic force microscopy probes modified by focused-ion-beam milling
|
journal | December 2004 |
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