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Biosensor method and system based on feature vector extraction

Patent ·
OSTI ID:1086740

A system for biosensor-based detection of toxins includes providing at least one time-dependent control signal generated by a biosensor in a gas or liquid medium, and obtaining a time-dependent biosensor signal from the biosensor in the gas or liquid medium to be monitored or analyzed for the presence of one or more toxins selected from chemical, biological or radiological agents. The time-dependent biosensor signal is processed to obtain a plurality of feature vectors using at least one of amplitude statistics and a time-frequency analysis. At least one parameter relating to toxicity of the gas or liquid medium is then determined from the feature vectors based on reference to the control signal.

Research Organization:
ORNL (Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States))
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-00OR22725
Assignee:
University of Tennessee Research Foundation (Knoxville, TN); UT-Battelle, LLC (Oak Ridge, TN)
Patent Number(s):
8,476,062
Application Number:
13/431,664
OSTI ID:
1086740
Country of Publication:
United States
Language:
English

References (10)

Particle detection by electrical impedance spectroscopy with asymmetric-polarization AC electroosmotic trapping journal April 2005
Biosensors for rapid monitoring of primary-source drinking water using naturally occurring photosynthesis journal October 2002
Development and evaluation of electrochemical glucose enzyme biosensors based on carbon film electrodes journal January 2005
An AC Electrokinetic Technique for Collection and Concentration of Particles and Cells on Patterned Electrodes journal July 2005
Stand-off tissue-based biosensors for the detection of chemical warfare agents using photosynthetic fluorescence induction journal September 2001
Development of infrared optical sensor for selective detection of tyrosine in biological fluids journal September 2005
Magnetic resonance as a technique to magnetic biosensors characterization in Neocapritermes opacus termites journal July 2005
Acoustic immunosensor for real-time sensing of neurotransmitter GABA conference January 2003
Ultrasensitive magnetic biosensor for homogeneous immunoassay journal December 2000
Long-Range AC Electroosmotic Trapping and Detection of Bioparticles journal April 2005

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