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Title: Biosensor method and system based on feature vector extraction

Abstract

A method of biosensor-based detection of toxins comprises the steps of providing at least one time-dependent control signal generated by a biosensor in a gas or liquid medium, and obtaining a time-dependent biosensor signal from the biosensor in the gas or liquid medium to be monitored or analyzed for the presence of one or more toxins selected from chemical, biological or radiological agents. The time-dependent biosensor signal is processed to obtain a plurality of feature vectors using at least one of amplitude statistics and a time-frequency analysis. At least one parameter relating to toxicity of the gas or liquid medium is then determined from the feature vectors based on reference to the control signal.

Inventors:
 [1];  [1];  [2]
  1. Knoxville, TN
  2. San Jose, CA
Publication Date:
Research Org.:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1040794
Patent Number(s):
8,158,377
Application Number:
11/216,282
Assignee:
UT-Battelle, LLC (Oak Ridge, TN)
DOE Contract Number:  
AC05-00OR22725
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Greenbaum, Elias, Rodriguez, Jr., Miguel, Qi, Hairong, and Wang, Xiaoling. Biosensor method and system based on feature vector extraction. United States: N. p., 2012. Web.
Greenbaum, Elias, Rodriguez, Jr., Miguel, Qi, Hairong, & Wang, Xiaoling. Biosensor method and system based on feature vector extraction. United States.
Greenbaum, Elias, Rodriguez, Jr., Miguel, Qi, Hairong, and Wang, Xiaoling. Tue . "Biosensor method and system based on feature vector extraction". United States. https://www.osti.gov/servlets/purl/1040794.
@article{osti_1040794,
title = {Biosensor method and system based on feature vector extraction},
author = {Greenbaum, Elias and Rodriguez, Jr., Miguel and Qi, Hairong and Wang, Xiaoling},
abstractNote = {A method of biosensor-based detection of toxins comprises the steps of providing at least one time-dependent control signal generated by a biosensor in a gas or liquid medium, and obtaining a time-dependent biosensor signal from the biosensor in the gas or liquid medium to be monitored or analyzed for the presence of one or more toxins selected from chemical, biological or radiological agents. The time-dependent biosensor signal is processed to obtain a plurality of feature vectors using at least one of amplitude statistics and a time-frequency analysis. At least one parameter relating to toxicity of the gas or liquid medium is then determined from the feature vectors based on reference to the control signal.},
doi = {},
url = {https://www.osti.gov/biblio/1040794}, journal = {},
number = ,
volume = ,
place = {United States},
year = {2012},
month = {4}
}

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Works referenced in this record:

Development of infrared optical sensor for selective detection of tyrosine in biological fluids
journal, September 2005


Biosensors for rapid monitoring of primary-source drinking water using naturally occurring photosynthesis
journal, October 2002


Magnetic resonance as a technique to magnetic biosensors characterization in Neocapritermes opacus termites
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Acoustic immunosensor for real-time sensing of neurotransmitter GABA
conference, January 2003


Stand-off tissue-based biosensors for the detection of chemical warfare agents using photosynthetic fluorescence induction
journal, September 2001


Ultrasensitive magnetic biosensor for homogeneous immunoassay
journal, December 2000