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Title: Materials and methods for efficient lactic acid production

Patent ·
OSTI ID:1083310
; ; ; ; ;

The present invention provides derivatives of Escherichia coli constructed for the production of lactic acid. The transformed E. coli of the invention are prepared by deleting the genes that encode competing pathways followed by a growth-based selection for mutants with improved performance. These transformed E. coli are useful for providing an increased supply of lactic acid for use in food and industrial applications.

Research Organization:
University of Florida Research Foundation, Inc. (Gainesville, FL)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-96ER20222; FG36-04GO14019
Assignee:
University of Florida Research Foundation, Inc. (Gainesville, FL)
Patent Number(s):
8,426,191
Application Number:
12/632,041
OSTI ID:
1083310
Country of Publication:
United States
Language:
English

References (21)

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Materials and methods for the efficient production of acetate and other products patent-application August 2004
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Deletion of methylglyoxal synthase gene (mgsA) increased sugar co-metabolism in ethanol-producing Escherichia coli journal May 2009
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Materials and methods for efficient lactic acid production patent December 2009
Recombinant Escherichia coli engineered for production of L-lactic acid from hexose and pentose sugars journal October 2001

Cited By (1)

Materials and methods for efficient lactic acid production patent April 2013

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