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Title: Laser heating of aqueous samples on a micro-optical-electro-mechanical system

Patent ·
OSTI ID:1083216

A system of heating a sample on a microchip includes the steps of providing a microchannel flow channel in the microchip; positioning the sample within the microchannel flow channel, providing a laser that directs a laser beam onto the sample for heating the sample; providing the microchannel flow channel with a wall section that receives the laser beam and enables the laser beam to pass through wall section of the microchannel flow channel without being appreciably heated by the laser beam; and providing a carrier fluid in the microchannel flow channel that moves the sample in the microchannel flow channel wherein the carrier fluid is not appreciably heated by the laser beam.

Research Organization:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC52-07NA27344
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA); The Board of Regents, The University of California (Oakland, CA)
Patent Number(s):
8,367,976
Application Number:
12/331,487
OSTI ID:
1083216
Country of Publication:
United States
Language:
English

References (7)

Non-contact radiant heating and temperature sensing device for a chemical reaction chamber patent December 2004
Chemical amplification based on fluid partitioning patent May 2006
Non-contact radiant heating and temperature sensing device for a chemical reaction chamber patent February 2007
Method and apparatus for the rapid disruption of cells or viruses using micro magnetic beads and laser patent December 2010
Method for performing crystallization and reactions in pressure-driven fluid plugs patent March 2011
Apparatus for chemical amplification based on fluid partitioning in an immiscible liquid patent May 2012
Monodispersed microfluidic droplet generation by shear focusing microfluidic device journal March 2006