Cellular and molecular level responses after radiofrequency radiation exposure, alone or in combination with x-rays or chemicals. Final report, 1 April 1991-30 September 1994

Technical Report · Tue Feb 21 04:00:00 EST 1995

OSTI ID:107837

Meltz, M L; Natarajan, M; Prasad, A V

This project was initiated to explore the potential bioeffects of microwave radiation, alone or in combination with ionizing radiation and chemicals. Over the time period of the project, an automated thermal control system, to be used for maintaining the temperature in tissue culture medium during microwave exposures, was designed, constructed, and software was created. While this was underway during the project period, numerous positive control biological experiments were performed on two different cell types, the Epstein Barr Virus transformed 244B human lymphoblastoid cell, and the freshly isolated peripheral human lymphocyte. The 244B cells were used to address the question of whether a physical agent, ionizing radiation, at low doses where cells would predominantly remain viable, would induce the DNA binding protein NF-kB, and/or four immediate early genes (IEG) (protooncogenes).

• Research Organization: Texas Univ. Health Science Center, San Antonio, TX (United States). Dept. of Radiology
• OSTI ID: 107837
• Report Number(s): AD-A--292488/4/XAB; CNN: Contract AFOSR-91-0206
• Country of Publication: United States
• Language: English

Related Subjects

56 BIOLOGY AND MEDICINE
APPLIED STUDIES
BIOLOGICAL RADIATION EFFECTS
CULTURE MEDIA
DNA
GENES
IONIZING RADIATIONS
LYMPHOCYTES
MELATONIN
MICROWAVE RADIATION
ONCOGENIC VIRUSES
X RADIATION