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Title: Biosensor method and system based on feature vector extraction

Patent ·
OSTI ID:1040794

A method of biosensor-based detection of toxins comprises the steps of providing at least one time-dependent control signal generated by a biosensor in a gas or liquid medium, and obtaining a time-dependent biosensor signal from the biosensor in the gas or liquid medium to be monitored or analyzed for the presence of one or more toxins selected from chemical, biological or radiological agents. The time-dependent biosensor signal is processed to obtain a plurality of feature vectors using at least one of amplitude statistics and a time-frequency analysis. At least one parameter relating to toxicity of the gas or liquid medium is then determined from the feature vectors based on reference to the control signal.

Research Organization:
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-00OR22725
Assignee:
UT-Battelle, LLC (Oak Ridge, TN)
Patent Number(s):
8,158,377
Application Number:
11/216,282
OSTI ID:
1040794
Country of Publication:
United States
Language:
English

References (7)

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Acoustic immunosensor for real-time sensing of neurotransmitter GABA conference January 2003
Stand-off tissue-based biosensors for the detection of chemical warfare agents using photosynthetic fluorescence induction journal September 2001
Ultrasensitive magnetic biosensor for homogeneous immunoassay journal December 2000