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Methods for magnetic resonance analysis using magic angle technique

Patent ·
OSTI ID:1032714
 [1];  [2];  [2];  [2]
  1. Richland, WA
  2. Kennewick, WA
+ Show Author Affiliations
Methods of performing a magnetic resonance analysis of a biological object are disclosed that include placing the object in a main magnetic field (that has a static field direction) and in a radio frequency field; rotating the object at a frequency of less than about 100 Hz around an axis positioned at an angle of about 54.degree.44' relative to the main magnetic static field direction; pulsing the radio frequency to provide a sequence that includes a phase-corrected magic angle turning pulse segment; and collecting data generated by the pulsed radio frequency. In particular embodiments the method includes pulsing the radio frequency to provide at least two of a spatially selective read pulse, a spatially selective phase pulse, and a spatially selective storage pulse. Further disclosed methods provide pulse sequences that provide extended imaging capabilities, such as chemical shift imaging or multiple-voxel data acquisition.
Research Organization:
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC06-76RL01830
Assignee:
Battelle Memorial Institute (Richland, WA)
Patent Number(s):
8,064,982
Application Number:
11/562,390
OSTI ID:
1032714
Country of Publication:
United States
Language:
English

References (3)

Localized in vivo isotropic-anisotropic correlation1H NMR spectroscopy using ultraslow magic angle spinning journal January 2005
Pulsed-field gradient nuclear magnetic resonance as a tool for studying translational diffusion: Part 1. Basic theory journal January 1997
Echo-planar imaging. journal September 1994

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