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U.S. Department of Energy
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Quantitative autoradiographic microimaging in the development and evaluation of radiopharmaceuticals

Conference ·
OSTI ID:10138162
 [1];  [2]
  1. Brookhaven National Lab., Upton, NY (United States)
  2. State Univ. of New York, Stony Brook, NY (United States)

Autoradiographic (ARG) microimaging is the method for depicting biodistribution of radiocompounds with highest spatial resolution. ARG is applicable to gamma, positron and negatron emitting radiotracers. Dual or multiple-isotope studies can be performed using half-lives and energies for discrimination of isotopes. Quantitation can be performed by digital videodensitometry and by newer filmless technologies. ARG`s obtained at different time intervals provide the time dimension for determination of kinetics.

Research Organization:
Brookhaven National Lab., Upton, NY (United States)
Sponsoring Organization:
USDOE, Washington, DC (United States)
DOE Contract Number:
AC02-76CH00016
OSTI ID:
10138162
Report Number(s):
BNL--60104; CONF-940172--1; ON: DE94009045
Country of Publication:
United States
Language:
English