The human genome project

Conference · Sat Jun 01 00:00:00 EDT 1991

OSTI ID:5922189

Bell, G I

The Human Genome Project will obtain high-resolution genetic and physical maps of each human chromosome and, somewhat later, of the complete nucleotide sequence of the deoxyribonucleic acid (DNA) in a human cell. The talk will begin with an extended introduction to explain the Project to nonbiologists and to show that map construction and sequence determination require extensive computation in order to determine the correct order of the mapped entities and to provide estimates of uncertainty. Computational analysis of the sequence data will become an increasingly important part of the project, and some computational challenges are described. 5 refs.

• Research Organization: Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
• Sponsoring Organization: USDOE; USDOE, Washington, DC (USA)
• DOE Contract Number: W-7405-ENG-36
• OSTI ID: 5922189
• Report Number(s): LA-UR-91-1372; CONF-9106179-1; ON: DE91011418
• Resource Relation: Conference: Supercomputing USA/Pacific 91, Santa Clara, CA (USA), 19-21 Jun 1991
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
CHROMOSOMES
GENETIC MAPPING
DNA SEQUENCING
INFORMATION NEEDS
MAN
CROSSING-OVER
DATA BASE MANAGEMENT
DNA
DNA-CLONING
DYNAMIC PROGRAMMING
GENES
MOLECULAR STRUCTURE
PARALLEL PROCESSING
ANIMALS
CLONING
DNA HYBRIDIZATION
HYBRIDIZATION
MAMMALS
MANAGEMENT
MAPPING
NUCLEIC ACIDS
ORGANIC COMPOUNDS
PRIMATES
PROGRAMMING
STRUCTURAL CHEMICAL ANALYSIS
VERTEBRATES
550400* - Genetics
550200 - Biochemistry