The human genome: Computational challenges
The deoxyribonucleic acid (DNA) of a human cell contains all the information required for specifying that cell, or indeed the whole person, and constitues the human genome. Programs are now underway to obtain genetic linkage maps and physical maps of human chromosomes containing the DNA, and large scale efforts will soon begin to provide detailed sequences. The challenges involved in assembling these data into a knowledge base are examined. Computations will play a key role in enabling the scientists to understand the information contained in sequence data. Pattern recognition and string matching algorithms will be of particular importance. Recent results in the use of adaptive networks for pattern detection will be presented. 19 refs.
- Research Organization:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- DOE Contract Number:
- W-7405-ENG-36
- OSTI ID:
- 5297174
- Report Number(s):
- LA-UR-88-450; CONF-880567-2; ON: DE88006465
- Resource Relation:
- Conference: 3. international conference on supercomputing, Boston, MA, USA, 15 May 1988
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
99 GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE
DNA SEQUENCING
INFORMATION NEEDS
KNOWLEDGE BASE
GENETIC MAPPING
MAN
ANIMALS
MAMMALS
MAPPING
PRIMATES
STRUCTURAL CHEMICAL ANALYSIS
VERTEBRATES
550400* - Genetics
550200 - Biochemistry
990300 - Information Handling