Bioluminescence monitor and method for enzymatic determinations. [Patents]

Patent · Tue Apr 28 00:00:00 EDT 1981

OSTI ID:5609413

Bostick, W. D.; Denton, M. S.; Dinsmore, S. R.

An on-line, nonreferenced apparatus for measuring the concentration of a biomarker species in authentic biological samples in solution comprises conduit means for conducting said sample solution from a source of said solution, stream diversion means disposed within the conduit for diverting a predetermined amount of said sample for analysis, means for introducing and independently regulating the flow of one or more reactants disposed in fluid communication with said diverted stream, incubating means within the diverted stream for reacting said reactants and biomarkers to produce a bioluminescence emission, and means disposed within the diverted stream for monitoring said emission intensity which is correlatable to said biomarker concentration.

• DOE Contract Number: W-7405-ENG-26
• Assignee: Dept. of Energy
• Application Number: ON: DE82007325
• OSTI ID: 5609413
• Country of Publication: United States
• Language: English

Related Subjects

47 OTHER INSTRUMENTATION
62 RADIOLOGY AND NUCLEAR MEDICINE
BIOLOGICAL INDICATORS
DIAGNOSTIC USES
MEASURING INSTRUMENTS
BIOLUMINESCENCE
MEASURING METHODS
FLUORESCENCE
ISOENZYMES
PROTEINS
AUTOMATION
EMISSION SPECTROSCOPY
FLUOROSCOPY
LIQUID COLUMN CHROMATOGRAPHY
BIOMEDICAL RADIOGRAPHY
CHROMATOGRAPHY
DIAGNOSTIC TECHNIQUES
LUMINESCENCE
MEDICINE
NUCLEAR MEDICINE
ORGANIC COMPOUNDS
RADIOLOGY
SEPARATION PROCESSES
SPECTROSCOPY
USES
440300* - Miscellaneous Instruments- (-1989)
550600 - Medicine