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Title: Genetically modified yeast species, and fermentation processes using genetically modified yeast

Patent ·
OSTI ID:1390173
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Yeast cells are transformed with an exogenous xylose isomerase gene. Additional genetic modifications enhance the ability of the transformed cells to ferment xylose to ethanol or other desired fermentation products. Those modifications include deletion of non-specific or specific aldose reductase gene(s), deletion of xylitol dehydrogenase gene(s) and/or overexpression of xylulokinase.

Research Organization:
Cargill Incorporated, Wayzata, MN (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FC07-02ID14349
Assignee:
Cargill Incorporated
Patent Number(s):
9,758,799
Application Number:
15/201,913
OSTI ID:
1390173
Resource Relation:
Patent File Date: 2016 Jul 05
Country of Publication:
United States
Language:
English

References (7)

Xylose utilization by recombinant yeasts patent February 1999
Genetically engineered yeast and mutants thereof for the efficient fermentation of lignocellulose hydrolysates patent June 2002
Xylose isomerase with improved properties patent November 2002
Production of ethanol from xylose patent June 2003
Genetically modified yeast of the species Issatchenkia orientalis and closely relates species, and fermentation processes using same patent January 2012
Lactic acid-producing yeast cells having nonfunctional L- or D-lactate:ferricytochrome C oxidoreductase cells patent March 2012
Cytosolic isobutanol pathway localization for the production of isobutanol patent July 2012

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