Triggered optical biosensor
Abstract
An optical biosensor is provided for the detection of a multivalent target biomolecule, the biosensor including a substrate having a bilayer membrane thereon, a recognition molecule situated at the surface, the recognition molecule capable of binding with the multivalent target biomolecule, the recognition molecule further characterized as including a fluorescence label thereon and as being movable at the surface and a device for measuring a fluorescence change in response to binding between the recognition molecule and the multivalent target biomolecule.
- Inventors:
-
- Los Alamos, NM
- Issue Date:
- Research Org.:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- OSTI Identifier:
- 874029
- Patent Number(s):
- 6297059
- Application Number:
- 09/338457
- Assignee:
- Regents of University of California (Los Alamos, NM)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE Y02A - TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- DOE Contract Number:
- W-7405-ENG-36
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- triggered; optical; biosensor; provided; detection; multivalent; target; biomolecule; including; substrate; bilayer; membrane; thereon; recognition; molecule; situated; surface; capable; binding; characterized; fluorescence; label; movable; device; measuring; change; response; bilayer membrane; optical biosensor; membrane thereon; /436/435/
Citation Formats
Song, Xuedong, and Swanson, Basil I. Triggered optical biosensor. United States: N. p., 2001.
Web.
Song, Xuedong, & Swanson, Basil I. Triggered optical biosensor. United States.
Song, Xuedong, and Swanson, Basil I. Mon .
"Triggered optical biosensor". United States. https://www.osti.gov/servlets/purl/874029.
@article{osti_874029,
title = {Triggered optical biosensor},
author = {Song, Xuedong and Swanson, Basil I},
abstractNote = {An optical biosensor is provided for the detection of a multivalent target biomolecule, the biosensor including a substrate having a bilayer membrane thereon, a recognition molecule situated at the surface, the recognition molecule capable of binding with the multivalent target biomolecule, the recognition molecule further characterized as including a fluorescence label thereon and as being movable at the surface and a device for measuring a fluorescence change in response to binding between the recognition molecule and the multivalent target biomolecule.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Jan 01 00:00:00 EST 2001},
month = {Mon Jan 01 00:00:00 EST 2001}
}
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