Fiber optic D dimer biosensor

Patent · Fri Jan 01 00:00:00 EST 1999

OSTI ID:872449

Glass, Robert S ^[1]; Grant, Sheila A ^[2]

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1. Livermore, CA
2. Pleasanton, CA

A fiber optic sensor for D dimer (a fibrinolytic product) can be used in vivo (e.g., in catheter-based procedures) for the diagnosis and treatment of stroke-related conditions in humans. Stroke is the third leading cause of death in the United States. It has been estimated that strokes and stroke-related disorders cost Americans between $15-30 billion annually. Relatively recently, new medical procedures have been developed for the treatment of stroke. These endovascular procedures rely upon the use of microcatheters. These procedures could be facilitated with this sensor for D dimer integrated with a microcatheter for the diagnosis of clot type, and as an indicator of the effectiveness, or end-point of thrombolytic therapy.

• Research Organization: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
• DOE Contract Number: W-7405-ENG-48
• Assignee: Regents of University of California (Oakland, CA)
• Patent Number(s): US 5938595
• OSTI ID: 872449
• Country of Publication: United States
• Language: English

Related Subjects

fiber
optic
dimer
biosensor
sensor
fibrinolytic
product
vivo
catheter-based
procedures
diagnosis
treatment
stroke-related
conditions
humans
stroke
third
leading
death
united
estimated
strokes
disorders
cost
americans
$15-30
billion
annually
relatively
recently
medical
developed
endovascular
rely
microcatheters
facilitated
integrated
microcatheter
clot
type
indicator
effectiveness
end-point
thrombolytic
therapy
medical procedures
fiber optic
optic sensor
stroke-related conditions
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