Effect of pulsed dose in simultaneous and sequential irradiation of V-79 cells by 14. 8 MeV neutrons and /sup 60/Co photons

Technical Report · Sat Jan 01 00:00:00 EST 1983

OSTI ID:5742341

Higgins, P D; DeLuca, Jr, P M; Gould, M N; Schell, M C; Pearson, D W

The effect of irradiating V-79 Chinese hamster ovary cells with a mixture of 40% 14.8-MeV neutrons and 60% /sup 60/Co photons with simultaneous or sequential exposures is investigated. Target doses are obtained by irradiating cell samples with 3-minute-long pulses of alternating neutrons and photons (in the sequential case) or with mixed neutrons and photons followed by equal beam-off periods to insure equal total-exposure times for sequenced and simultaneous irradiations. We observe qualitative differences between the survival results under each beam configuration that confirms earlier observations.

• Research Organization: Wisconsin Univ., Madison (USA). Dept. of Human Oncology; Wisconsin Univ., Madison (USA). Dept. of Medical Physics
• DOE Contract Number: AC02-76EV01105
• OSTI ID: 5742341
• Report Number(s): DOE/EV/01105-302; ON: DE83017602
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CHO CELLS
SURVIVAL CURVES
GAMMA RADIATION
BIOLOGICAL RADIATION EFFECTS
NEUTRONS
CELL CULTURES
COMPARATIVE EVALUATIONS
EXPERIMENTAL DATA
FRACTIONATED IRRADIATION
IRRADIATION PROCEDURES
PULSES
RADIATION DOSES
ANIMAL CELLS
BARYONS
BIOLOGICAL EFFECTS
DATA
DOSES
ELECTROMAGNETIC RADIATION
ELEMENTARY PARTICLES
FERMIONS
HADRONS
INFORMATION
IONIZING RADIATIONS
IRRADIATION
NUCLEONS
NUMERICAL DATA
RADIATION EFFECTS
RADIATIONS
560121* - Radiation Effects on Cells- External Source- (-1987)