A review of ground-based heavy-ion radiobiology relevant to space radiation risk assessment: Part II. Cardiovascular and immunological effects

Journal Article · Mon Feb 26 00:00:00 EST 2007 · Advances in Space Research

DOI:https://doi.org/10.1016/j.asr.2007.05.071· OSTI ID:938417

Blakely, Eleanor A; Chang, Polly Y

The future of manned space flight depends on an analysis of the numerous potential risks of travel into deep space. Currently no radiation dose limits have been established for these exploratory missions. To set these standards more information is needed about potential acute and late effects on human physiology from appropriate radiation exposure scenarios, including pertinent radiation types and dose rates. Cancer risks have long been considered the most serious late effect from chronic daily relatively low-dose exposures to the complex space radiation environment. However, other late effects from space radiation exposure scenarios are under study in ground-based accelerator facilities and have revealed some unique particle radiation effects not observed with conventional radiations. A comprehensive review of pertinent literature that considers tissue effects of radiation leading to functional detriments in specific organ systems has recently been published (NCRP National Council on Radiation Protection and Measurements, Information Needed to Make Radiation Protection Recommendations for Space Missions Beyond Low-Earth Orbit, Report 153, Bethesda, MD, 2006). This paper highlights the review of two non-cancer concerns from this report: cardiovascular and immunological effects.

• Research Organization: Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
• Sponsoring Organization: Life Sciences Division
• DOE Contract Number: DE-AC02-05CH11231
• OSTI ID: 938417
• Report Number(s): LBNL-925E; TRN: US0901799
• Journal Information: Advances in Space Research, Vol. 40, Issue 4
• Country of Publication: United States
• Language: English

Related Subjects

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ACCELERATOR FACILITIES
DOSE RATES
FUNCTIONALS
NEOPLASMS
ORGANS
PHYSIOLOGY
RADIATION DOSES
RADIATION EFFECTS
RADIATION PROTECTION
RADIATIONS
RADIOBIOLOGY
RECOMMENDATIONS
RISK ASSESSMENT
SPACE FLIGHT
space radiation
heavy ions
acute and late radiation effects
risk assessment
cardiovascular radiation effects
immunological radiation effects