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Title: Compositions and methods for cancer treatment using targeted carbon nanotubes

Patent ·
OSTI ID:1333826
; ;

Compositions for detecting and/or destroying cancer tumors and/or cancer cells via photodynamic therapy are disclosed, as well as methods of use thereof. The compositions comprise a linking protein or peptide attached to or otherwise physically associated with a carbon nanotube to form a targeted protein-carbon nanotube complex.

Research Organization:
Univ. of Oklahoma, Norman, OK (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-06ER64239
Assignee:
The Board of Regents of the University of Oklahoma (Norman, OK)
Patent Number(s):
9,504,745
Application Number:
14/100,892
OSTI ID:
1333826
Resource Relation:
Patent File Date: 2013 Dec 09
Country of Publication:
United States
Language:
English

References (13)

Annexins: From Structure to Function journal April 2002
Heating the patient: a promising approach? journal August 2002
Enhanced systems and methods for RF-induced hyperthermia patent March 2009
Carbon nanotube-enhanced thermal destruction of cancer cells in a noninvasive radiofrequency field: Nanotube Heating Kills Cancer Cells journal October 2007
Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction journal August 2005
Compositions and methods for cancer treatment using targeted carbon nanotubes patent August 2013
High contrast optoacoustic imaging using nanoparticles patent March 2009
Combined methods for tumor vasculature targeting and tumor treatment with radiotherapy patent October 2006
Tailoring ( n , m ) Structure of Single-Walled Carbon Nanotubes by Modifying Reaction Conditions and the Nature of the Support of CoMo Catalysts journal February 2006
Cellulose derivatives as excellent dispersants for single-wall carbon nanotubes as demonstrated by absorption and photoluminescence spectroscopy journal February 2006
Encapsulation of nanotubes via self-assembled nanostructures patent May 2005
Combined cancer treatment methods using antibodies to aminophospholipids patent September 2008
Immunization with Peptide-Functionalized Carbon Nanotubes Enhances Virus-Specific Neutralizing Antibody Responses journal October 2003

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Related Subjects

59 BASIC BIOLOGICAL SCIENCES
60 APPLIED LIFE SCIENCES