skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Association between Electronic Cigarette Use and Asthma among High School Students in South Korea

Journal Article · · PLoS ONE
 [1];  [2]
  1. Hanyang Women's Univ., Seoul (Korea, Republic of). Dept. of Public Health Administration
  2. Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

Little is known about health outcomes related to electronic cigarette (EC) use, despite its growing popularity. The aim of this study is to investigate the association between EC use and asthma. The study design is a cross-sectional study. A total of 35,904 high school students were included as the final study population. The presence of asthma was based on a student’s self-reported doctor diagnosis of asthma in the past 12 months. Results showed prevalence rates of asthmatics in ‘current EC users’ (n = 2,513), ‘former EC users’ (n = 2,078), and ‘never EC users’ (n = 31,313), were 3.9% (n = 98), 2.2% (n = 46) and 1.7% (n = 530), respectively. Comparing ‘current EC’ users with ‘never EC’ users, the unadjusted OR for asthma was 2.36 (95% CI: 1.89–2.94). In order to control for the effect of conventional cigarette (CC) smoking, after stratifying the subjects by the three CC smoking categories (never CC, former CC, and current CC), within the ‘never CC’ category, the unadjusted OR for asthma for ‘current EC’ users was 3.41 (95% CI: 1.79–6.49), and the adjusted OR was 2.74 (95% CI: 1.30–5.78). Severe asthma was reflected by the number of days absent from school due to asthma symptoms; current EC users had the highest adjusted OR for severe asthma compared to ‘never EC’ users. In conclusion, when compared to a reference population of high school students in South Korea, EC users have an increased association with asthma and are more likely to have had days absent from school due to severe asthma symptoms. In conclusion, the results indicate that EC use may be a risk factor for asthma. The results may be useful in developing a scientific basis for the evaluation of a potential health hazard by EC.

Research Organization:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Sponsoring Organization:
USDOE; Hanyang Women's University (Republic of Korea)
OSTI ID:
1259659
Journal Information:
PLoS ONE, Vol. 11, Issue 3; ISSN 1932-6203
Publisher:
Public Library of ScienceCopyright Statement
Country of Publication:
United States
Language:
English
Citation Metrics:
Cited by: 131 works
Citation information provided by
Web of Science

References (26)

Metal and Silicate Particles Including Nanoparticles Are Present in Electronic Cigarette Cartomizer Fluid and Aerosol journal March 2013
The Renormalization of Smoking? E-Cigarettes and the Tobacco “Endgame” journal January 2014
Electronic cigarette use among adult population: a cross-sectional study in Barcelona, Spain (2013-2014) journal August 2014
Electronic Cigarette Use Among Korean Adolescents: A Cross-Sectional Study of Market Penetration, Dual Use, and Relationship to Quit Attempts and Former Smoking journal June 2014
Electronic-Cigarette Smoking Experience Among Adolescents journal November 2011
Characteristics, Perceived Side Effects and Benefits of Electronic Cigarette Use: A Worldwide Survey of More than 19,000 Consumers journal April 2014
Real-world effectiveness of e-cigarettes when used to aid smoking cessation: a cross-sectional population study: Real-world effectiveness of e-cigarettes journal August 2014
Hidden Formaldehyde in E-Cigarette Aerosols journal January 2015
Chemical evaluation of electronic cigarettes journal April 2014
Levels of selected carcinogens and toxicants in vapour from electronic cigarettes journal March 2013
Associations between selected allergens, phthalates, nicotine, polycyclic aromatic hydrocarbons, and bedroom ventilation and clinically confirmed asthma, rhinoconjunctivitis, and atopic dermatitis in preschool children journal August 2013
Endothelial disruptive proinflammatory effects of nicotine and e-cigarette vapor exposures journal July 2015
Asthma in older adults journal September 2010
Asthma medication use among U.S. adults 18 and older journal November 2014
Smoking and asthma: dangerous liaisons journal August 2012
Cigarette smoking is associated with a greater risk of incident asthma in allergic rhinitis journal June 2008
Electronic Cigarette Liquid Increases Inflammation and Virus Infection in Primary Human Airway Epithelial Cells journal September 2014
Comparison of the phagocytic response of rat and hamster alveolar macrophages to man-made vitreous fibers in vitro journal November 2000
Electronic Cigarettes and Conventional Cigarette Use Among US Adolescents: A Cross-sectional Study journal July 2014
Evaluating the Control Banding Nanotool: a qualitative risk assessment method for controlling nanoparticle exposures journal June 2009
Differential Responses of Rat Alveolar and Peritoneal Macrophages to Man-Made Vitreous Fibers in Vitro journal March 2001
The Renormalization of Smoking? E-Cigarettes and the Tobacco “Endgame” [Correction] journal June 2014
Tobacco Control Policy and Electronic Cigarettes journal July 2014
Youth vaping: a review and update on global epidemiology, physical and behavioral health risks, and clinical considerations journal August 2021
Amorphous silica nanoparticles impair vascular homeostasis and induce systemic inflammation journal June 2014
Inhallation of e-Cigarette Cartridge Solution Aggravates Allergen-induced Airway Inflammation and Hyper-responsiveness in Mice journal March 2014

Cited By (29)

Electronic Cigarettes: Their Constituents and Potential Links to Asthma journal October 2017
Acute Effects of Electronic Cigarette Inhalation on the Vasculature and the Conducting Airways journal April 2019
The Use of Heated Tobacco Products is Associated with Asthma, Allergic Rhinitis, and Atopic Dermatitis in Korean Adolescents journal November 2019
Physicochemical studies of direct interactions between lung surfactant and components of electronic cigarettes liquid mixtures journal April 2018
Factors Associated with Electronic Cigarette Use among Young Adults: The French “Trajectoires EpidéMiologiques en POpulation” (TEMPO) Cohort Study journal January 2020
How close are we to definitively identifying the respiratory health effects of e-cigarettes? journal June 2018
The effect of e-cigarette aerosol emissions on respiratory health: a narrative review journal July 2019
How do we determine the impact of e-cigarettes on cigarette smoking cessation or reduction? Review and recommendations for answering the research question with scientific rigor: E-cigarettes and smoking cessation or reduction journal October 2017
Short-term respiratory effects of e-cigarettes in healthy individuals and smokers with asthma: E-cigarette effects in healthy and asthmatics journal September 2017
What are the respiratory effects of e-cigarettes? journal September 2019
Pulmonary toxicity of e-cigarettes journal August 2017
Electronic Cigarette Use and Respiratory Symptoms in Adolescents journal April 2017
Electronic cigarette use in youths: a position statement of the Forum of International Respiratory Societies journal May 2018
The association between e-cigarette use and asthma among never combustible cigarette smokers: behavioral risk factor surveillance system (BRFSS) 2016 & 2017 journal October 2019
Hypothesis: may e-cigarette smoking boost the allergic epidemic? journal November 2016
The association between electronic-cigarette use and self-reported oral symptoms including cracked or broken teeth and tongue and/or inside-cheek pain among adolescents: A cross-sectional study journal July 2017
Relationship between spending on electronic cigarettes, 30-day use, and disease symptoms among current adult cigarette smokers in the U.S. journal November 2017
Association between Electronic Cigarette Use and Asthma in Never-Smokers journal November 2019
Adult E-Cigarettes Use Associated with a Self-Reported Diagnosis of COPD journal October 2019
Electronic Cigarettes: Their Constituents and Potential Links to Asthma text January 2017
Factors Associated with Electronic Cigarette Use among Young Adults: The French “Trajectoires EpidéMiologiques en POpulation” (TEMPO) Cohort Study text January 2020
Physicochemical studies of direct interactions between lung surfactant and components of electronic cigarettes liquid mixtures text January 2018
What are the respiratory effects of e-cigarettes? [Correction] journal October 2019
Factors Associated with Electronic Cigarette Use among Young Adults: The French “Trajectoires EpidéMiologiques en POpulation” (TEMPO) Cohort Study text January 2020
Association of Electronic Cigarette Use With Smoking Habits, Demographic Factors, and Respiratory Symptoms journal July 2018
Active, passive, and electronic cigarette smoking is associated with asthma in adolescents journal December 2017
Nonhuman Primate Models of Respiratory Disease: Past, Present, and Future journal December 2017
E-Cigarettes: Use, Effects on Smoking, Risks, and Policy Implications journal April 2018
Awareness, current use of electronic cigarettes and associated smoking factors in Zhejiang Chinese adolescents journal October 2019

Similar Records

Association between indoor and outdoor air pollution and adolescent asthma from 1995 to 1996 in Taiwan
Journal Article · Fri Oct 01 00:00:00 EDT 1999 · Environmental Research · OSTI ID:1259659

Association of pediatric asthma severity with exposure to common household dust allergens
Journal Article · Sat Aug 15 00:00:00 EDT 2009 · Environmental Research · OSTI ID:1259659

Decreasing trend in passive tobacco smoke exposure and association with asthma in U.S. children
Journal Article · Mon Oct 15 00:00:00 EDT 2018 · Environmental Research · OSTI ID:1259659

Related Subjects