The Intrinsic Apoptosis Pathways as a Target in Anticancer Therapy
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May 2012 |
The CUL4 Enigma: Culling DNA Repair Factors
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May 2009 |
Comprehensive characterization of the DNA amplification at 13q34 in human breast cancer reveals TFDP1 and CUL4A as likely candidate target genes
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December 2009 |
Lung tumourigenesis in a conditional Cul4A transgenic mouse model : Cul4A in lung tumourigenesis
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May 2014 |
CUL4A Induces Epithelial–Mesenchymal Transition and Promotes Cancer Metastasis by Regulating ZEB1 Expression
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December 2013 |
Nuclear EGFR protein expression predicts poor survival in early stage non-small cell lung cancer
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July 2013 |
Human homologue for Caenorhabditis elegans CUL-4 protein overexpression is associated with malignant potential of epithelial ovarian tumours and poor outcome in carcinoma
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March 2012 |
Comparative genomic hybridization of squamous cell carcinoma of the esophagus: The possible involvement of theDP1 gene in the 13q34 amplicon
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April 1999 |
EGFR lung cancer mutants get specialized
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September 2013 |
Erlotinib alone or with bevacizumab as first-line therapy in patients with advanced non-squamous non-small-cell lung cancer harbouring EGFR mutations (JO25567): an open-label, randomised, multicentre, phase 2 study
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October 2014 |
An Evolutionarily Conserved Function of Proliferating Cell Nuclear Antigen for Cdt1 Degradation by the Cul4-Ddb1 Ubiquitin Ligase in Response to DNA Damage
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January 2006 |
TFDP1, CUL4A, andCDC16 identified as targets for amplification at 13q34 in hepatocellular carcinomas
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June 2002 |
Cancer cell apoptotic pathways mediated by PEDF: prospects for therapy
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October 2009 |
Social variations in access to hospital care for patients with colorectal, breast, and lung cancer between 1999 and 2006: retrospective analysis of hospital episode statistics
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January 2010 |
Should epidermal growth factor receptor tyrosine kinase inhibitors be considered ideal drugs for the treatment of selected advanced non-small cell lung cancer patients?
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August 2013 |
CUL4A Abrogation Augments DNA Damage Response and Protection against Skin Carcinogenesis
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May 2009 |
Cul4A is an oncogene in malignant pleural mesothelioma
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February 2011 |
CRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growth
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September 2013 |
Epidermal Growth Factor Receptor Protects Proliferating Cell Nuclear Antigen from Cullin 4A Protein-mediated Proteolysis
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June 2012 |
An Evolutionarily Conserved Function of Proliferating Cell Nuclear Antigen for Cdt1 Degradation by the Cul4-Ddb1 Ubiquitin Ligase in Response to DNA Damage
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January 2006 |
Oncogenic CUL4A determines the response to thalidomide treatment in prostate cancer
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March 2012 |
Prognostic Value of EGFR Mutation and ERCC1 in Patients with Non-Small Cell Lung Cancer Undergoing Platinum-Based Chemotherapy
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August 2013 |
A Cul4 E3 Ubiquitin Ligase Regulates Histone Hand-Off during Nucleosome Assembly
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November 2013 |
Importance of the cytological samples for the epidermal growth factor receptor gene mutation test for non-small cell lung cancer
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January 2013 |
The diagnostic accuracy of pleural effusion and plasma samples versus tumour tissue for detection of EGFR mutation in patients with advanced non-small cell lung cancer: comparison of methodologies
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July 2013 |
Genetic Alterations in Childhood Medulloblastoma Analyzed by Comparative Genomic Hybridization
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January 2002 |
Cancer statistics, 2012
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journal
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January 2012 |
Role of Epidermal Growth Factor Receptor Inhibitors in Epidermal Growth Factor Receptor Wild-Type Non–Small-Cell Lung Cancer
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journal
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March 2013 |
Les thérapies ciblées dans la cancérologie digestive
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journal
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August 2012 |
Chemotherapeutic Targeting of Cell Death Pathways
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March 2012 |
Cul4A targets p27 for degradation and regulates proliferation, cell cycle exit, and differentiation during erythropoiesis
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June 2006 |
Combination therapy with anti-ErbB3 monoclonal antibodies and EGFR TKIs potently inhibits Non-small Cell Lung Cancer
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July 2013 |
Adrenocortical carcinoma is characterized by a high frequency of chromosomal gains and high-level amplifications
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June 2000 |
CRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growth
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January 2013 |
What new therapeutic targets exist for EGFR-mutant NSCLC?
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October 2014 |
Cullin 4A-mediated Proteolysis of DDB2 Protein at DNA Damage Sites Regulates in Vivo Lesion Recognition by XPC
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March 2006 |
CDK Inhibitor p21 Is Degraded by a Proliferating Cell Nuclear Antigen-coupled Cul4-DDB1 Cdt2 Pathway during S Phase and after UV Irradiation
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August 2008 |
Cul4A Physically Associates with MDM2 and Participates in the Proteolysis of p53
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November 2004 |
New Targetable Oncogenes in Non–Small-Cell Lung Cancer
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March 2013 |
Pathogenic Role of the CRL4 Ubiquitin Ligase in Human Disease
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January 2012 |
Lung Cancer Genotype-Based Therapy and Predictive Biomarkers: Present and Future
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December 2012 |