Fundamentals of ultrananocrystallie diamond (UNCD) thin films as biomaterials for developmental biology : embryonic fibroblasts growth on the surface of (UNCD) films.
Ultrananocrystalline diamond (UNCD) films possess numerous valuable good physical, chemical and mechanical properties, making UNCD an excellent material for implantable biodevices. However, one very important property required for biomaterials i.e., biocompatibility has not been studied for UNCD. In this research, biocompatible UNCD films were synthesized. It was found that UNCD film coated substrates can dramatically promote the growth of mouse embryonic fibroblasts (MEFs), while the uncoated substrates inhabit cell attachment. Through analyzing the microstructure and the surface chemistry of UNCD, the mechanisms of cell growth on UNCD were investigated. Given the unique properties of UNCD on inertness and toughness, the results consolidate UNCD film as the leading coating candidate for the next generation of medical implanted devices.
- Research Organization:
- Argonne National Lab. (ANL), Argonne, IL (United States)
- Sponsoring Organization:
- USDOE Office of Science (SC)
- DOE Contract Number:
- DE-AC02-06CH11357
- OSTI ID:
- 992825
- Report Number(s):
- ANL/MSD/CP-62423; TRN: US201022%%523
- Journal Information:
- Diamond Related Mater., Vol. 18, Issue Sep. 13, 2008; Conference: 2nd International Conference on New Diamond and Nano Carbons; May 26, 2008 - May 29, 2008; Taipei, Taiwan
- Country of Publication:
- United States
- Language:
- ENGLISH
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