BioXyce : an engineering platform for the study of cellular systems.
Journal Article
·
· Proposed for publication in IET Systems Biology.
OSTI ID:951515
Researchers use constructs from the field of electrical engineering for the modeling and analysis of biological systems, but few exploit parallels between electrical and biological circuits for simulation purposes. The authors discuss the development of BioXyce, a circuit-based biological simulation platform that uses Xyce, a large-scale electrical circuit simulator, as its simulation engine. BioXyce is capable of simulating whole-cell and multicellular systems. Simulation results for the central metabolism in Escherichia coli K12 and cellular differentiation in Drosophila sp. are presented.
- Research Organization:
- Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC04-94AL85000
- OSTI ID:
- 951515
- Report Number(s):
- SAND2008-7261J; TRN: US200912%%1
- Journal Information:
- Proposed for publication in IET Systems Biology., Journal Name: Proposed for publication in IET Systems Biology.
- Country of Publication:
- United States
- Language:
- English
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