skip to main content

Title: Isolation of Discrete Nanoparticle-DNA Conjugates for Plasmonic Applications

Discrete DNA-gold nanoparticle conjugates with DNA lengths as short as 15 bases for both 5 nm and 20 nm gold particles have been purified by anion-exchange HPLC. Conjugates comprising short DNA (<40 bases) and large gold particles (>_ 20 nm) are difficult to purify by other means, and are potential substrates for plasmon coupling experiments. Conjugate purity is demonstrated by hybridizing complementary conjugates to form discrete structures, which are visualized by TEM.
Authors:
; ; ; ; ;
Publication Date:
OSTI Identifier:
927872
Report Number(s):
LBNL-194E
TRN: US200816%%1105
DOE Contract Number:
DE-AC02-05CH11231
Resource Type:
Journal Article
Resource Relation:
Journal Name: Nano Letters; Journal Volume: 8; Journal Issue: 4; Related Information: Journal Publication Date: April 2008
Research Org:
Ernest Orlando Lawrence Berkeley National Laboratory, Berkeley, CA (US)
Sponsoring Org:
Materials Sciences Division
Country of Publication:
United States
Language:
English
Subject:
36; DNA; GOLD; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; PLASMONS; SUBSTRATES GOLD, NANOPARTICLE, NANOCRYSTAL, PLASMON, DNA, HPLC, ANION-EXCHANGE, BIOCONJUGATE, SELF-ASSEMBLY