Scintigraphic appearance of focal fatty infiltration of the liver using single-photon emission computed tomography

Conference · Sun Jan 01 00:00:00 EST 1984 · J. Nucl. Med.; (United States)

OSTI ID:7090020

Kudo, M; Hirasa, M; Ibuki, Y; Takakuwa, H; Fujimi, K; Veda, S; Tomita, S; Komori, H; Todo, A; Kitaura, Y

Fatty infiltration of the liver had been considered to assume a uniform distribution until quite recently. However, the development of X-ray computed tomography (XCT) and the ultrasound (US) has proven that fatty infiltration of the liver may sometimes assume a nonuniform distribution (focal fatty infiltration (FFI)). This investigation was undertaken to evaluate the scintigraphic appearance of FFI using single-photon emission computed tomography (SPECT) with a GE Maxicamera 400T. Radionuclide images including SPECT were evaluated in 12 cases with FFI which were diagnosed by XCT and US. Most of them were histrogically confirmed to be positive fatty infiltration in the liver. The results were as follows. The fatty infiltrated area was visualized as a hot spot in one case, a defect in 2 cases, a low uptake in one case and a normal uptake in 8 cases. Radionuclide imaging of FFI shows a large variety of findings and it suggests that Kupffer cell function varies with the causes or stage of fatty infiltration. And one can understand the pathological state of FFI from a viewpoint of Kupffer cell function only by radionuclide imaging including SPECT, which is very useful to compare the images with XCT images.

• Research Organization: Kyoto Univ., School of Medicine, Kyoto
• OSTI ID: 7090020
• Report Number(s): CONF-840619-; TRN: 87-008802
• Journal Information: J. Nucl. Med.; (United States), Vol. 25:5; Conference: 31. annual meeting of the Society of Nuclear Medicine, Los Angeles, CA, USA, 5 Jun 1984
• Country of Publication: United States
• Language: English

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