A biokinetic model for [sup 222]Rn gas distribution and alpha dose in humans following ingestion

Journal Article · Sat Jan 01 00:00:00 EST 1994 · Environment International; (United States)

DOI:https://doi.org/10.1016/0160-4120(94)90006-X· OSTI ID:7066084

Harley, N H; Robbins, E S ^[1]

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1. New York Univ. Medical School, NY (United States)

A biokinetic model for absorption and distribution of [sup 222]Rn in the body following ingestion in drinking water was developed. The rate parameters for the model are derived from historical human data reported in experiments of Harley et al. (1958) and Hursh et al. (1965). The biokinetic model fits the human data of Hursh et al. well for whole body retention following ingestion of [sup 222]Rn in water on an empty stomach. The equivalent dose to stem cells for stomach and colon cancer is estimated to be 1.6 [times] 10[sup [minus]9] Sv Bq[sup [minus]1]. The model calculations yield 4 and 3 calculated stomach and colon cancers from continuous intake of water at the estimated US average of 5.5 Bq L[sup [minus]1]. 16 refs., 3 figs., 2 tabs.

• OSTI ID: 7066084
• Journal Information: Environment International; (United States), Vol. 20:5; ISSN 0160-4120
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
RADON 222
ABSORPTION
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BIOLOGICAL MODELS
RETENTION
ALPHA DECAY RADIOISOTOPES
DAYS LIVING RADIOISOTOPES
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