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Title: Fibrosarcoma after high energy radiation therapy for pituitary adenoma

Pituitary sarcoma is a rare late complication of radiotherapy for pituitary tumors. Although early case reports involved multiple courses of relatively low-energy radiation therapy, pituitary sarcoma has been seen with single courses of high-energy x-ray or heavy particle radiotherapy. This report describes a fibrosarcoma of the pituitary occurring 5 years after 4,500 rad (45 Gy) of x-irradiation delivered in 20 treatments over 3 weeks by an 8 MeV linear accelerator.
Authors:
 [1] ; ; ;
  1. (Univ. of Virginia Medical Center, Charlottesville, VA)
Publication Date:
OSTI Identifier:
7056844
Resource Type:
Journal Article
Resource Relation:
Journal Name: Am. J. Roentgenol.; (United States); Journal Volume: 135:5
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; FIBROSARCOMAS; RADIOINDUCTION; PITUITARY GLAND; DELAYED RADIATION EFFECTS; ADENOMAS; MEV RANGE 01-10; PATIENTS; RADIOTHERAPY; SIDE EFFECTS; X RADIATION; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; DISEASES; ELECTROMAGNETIC RADIATION; ENDOCRINE GLANDS; ENERGY RANGE; GLANDS; IONIZING RADIATIONS; MEDICINE; MEV RANGE; NEOPLASMS; NUCLEAR MEDICINE; ORGANS; RADIATION EFFECTS; RADIATIONS; RADIOLOGY; SARCOMAS; THERAPY 560151* -- Radiation Effects on Animals-- Man; 550603 -- Medicine-- External Radiation in Therapy-- (1980-)