Detection of pulmonary aspiration in children with gastroesophageal reflux
The presence of pulmonary aspiration (PA) should be suspected in two groups of patients; those with symptoms of gastroesophageal reflux (GER) and pulmonary disease and patient's with pulmonary symptoms without signs of GER in whom other etiologies of pulmonary disease have been excluded. To determine if PA could be diagnosed in children using radionuclides 114 patients aged 3-12 months drank 500 ..mu..Ci of Tc-99m sulfur colloid mixed with infant formula and an additional 1.5 mCi was administered in the evening. All medicine was suspended 24 hours before. Images of the chest in supine position (ant, post views) were acquired on computer in 32 x 32 (byte mode) during 5 min each view at 2 and 18 hours. No outside pressure was applied. None of the patients with digestive symptomatology alone had positive exam. Of 88 patients with bronchopulmonary symptomatology 35 had abnormal examination 35% with moderate symptom were (Abn) and 55% with severe disease were abnormal. The radionuclide method appears to be the ideal study in patients where PA is suspected. The positivity of the method depends on the group of patients selected. The sensitivity is highest in patients with marked symptomatology.
- Research Organization:
- Univ. of Chile Hospital, Santiago
- OSTI ID:
- 7031624
- Report Number(s):
- CONF-850611-; TRN: 87-010693
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 26:5; Conference: 32. annual meeting of the Society of Nuclear Medicine, Houston, TX, USA, 2 Jun 1985
- Country of Publication:
- United States
- Language:
- English
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CHEST
SCINTISCANNING
LUNGS
RESPIRATORY SYSTEM DISEASES
DIAGNOSIS
DISEASE INCIDENCE
BIOMEDICAL RADIOGRAPHY
CARDIOVASCULAR SYSTEM
DIAGNOSTIC USES
DIGESTIVE SYSTEM DISEASES
ESOPHAGUS
GASTROINTESTINAL TRACT
INFANTS
PATIENTS
RADIOCOLLOIDS
RADIOPHARMACEUTICALS
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TECHNETIUM 99
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BETA-MINUS DECAY RADIOISOTOPES
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CHILDREN
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DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
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DISPERSIONS
DRUGS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
MEDICINE
NUCLEAR MEDICINE
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550601* - Medicine- Unsealed Radionuclides in Diagnostics