Practical dosimetric aspects of blood and blood product irradiation
Journal Article
·
· Transfusion (Philadelphia); (United States)
The method of choice to reduce susceptibility to transfusion-transmitted graft-versus-host disease is irradiation of allogenic blood and blood products for transfusion to immunosuppressed recipients. Optimal irradiation requires delivery of a known and homogeneous absorbed dose. The use of absorbed dose in air measured at the center of the irradiation volume without proper compensation for sample absorption can lead to approximately 20 percent underexposure. A lucite cylinder was used to provide the delivery of a homogeneous irradiation dose to blood products of different volumes by allowing rotation of the product.
- Research Organization:
- Children's Hospital National Medical Center, Washington, DC
- OSTI ID:
- 6989758
- Journal Information:
- Transfusion (Philadelphia); (United States), Vol. 5
- Country of Publication:
- United States
- Language:
- English
Similar Records
Effect of total lymphoid irradiation and pretransplant blood transfusion on pancreatic islet allograft survival
Pretransfusion blood irradiation: Clinical rationale and dosimetric considerations
Engraftment of allogeneic bone marrow without graft-versus-host disease in mongrel dogs using total lymphoid irradiation
Journal Article
·
Sun May 01 00:00:00 EDT 1983
· J. Surg. Res.; (United States)
·
OSTI ID:6989758
Pretransfusion blood irradiation: Clinical rationale and dosimetric considerations
Journal Article
·
Fri May 01 00:00:00 EDT 1992
· Medical Physics; (United States)
·
OSTI ID:6989758
Engraftment of allogeneic bone marrow without graft-versus-host disease in mongrel dogs using total lymphoid irradiation
Journal Article
·
Sun Jun 01 00:00:00 EDT 1980
· Transplantation; (United States)
·
OSTI ID:6989758
+2 more
Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BLOOD
IRRADIATION PROCEDURES
GRAFT-HOST REACTION
IMMUNOSUPPRESSION
IN VITRO
IRRADIATION
RADIATION DOSES
TRANSFUSIONS
BIOLOGICAL MATERIALS
BODY FLUIDS
DOSES
MATERIALS
THERAPY
560151* - Radiation Effects on Animals- Man
560130 - Radiation Effects on Microorganisms
BLOOD
IRRADIATION PROCEDURES
GRAFT-HOST REACTION
IMMUNOSUPPRESSION
IN VITRO
IRRADIATION
RADIATION DOSES
TRANSFUSIONS
BIOLOGICAL MATERIALS
BODY FLUIDS
DOSES
MATERIALS
THERAPY
560151* - Radiation Effects on Animals- Man
560130 - Radiation Effects on Microorganisms