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Title: Capillary liquid chromatography using laser-based and mass spectrometric detection. [Capillary zone electrophoresis (CZE); micellar electrokinetic capillary kchromatography (MECC)]

In the years following the 1986 seminal paper (J. Chromatogr. Sci., 24, 347-352) describing modern capillary zone electrophoresis (CZE), the prominence of capillary electrokinetic separation techniques has grown. A related electrochromatographic technique is micellar electrokinetic capillary chromatography (MECC). This report presents a brief synopsis of research efforts during the current 3-year period. In addition to a description of analytical separations-based research, results of efforts to develop and expand spectrometric detection for the techniques is reviewed. Laser fluorometric detection schemes have been successfully advanced. Mass spectrometric research was less fruitful, largely owing to personnel limitations. A regenerable fiber optic sensor was developed that can be used to remotely monitor chemical carcinogens, etc. (DLC)
Authors:
;
Publication Date:
OSTI Identifier:
6977773
Report Number(s):
DOE/ER/13613-36
ON: DE92040524
DOE Contract Number:
FG05-86ER13613
Resource Type:
Technical Report
Research Org:
Tennessee Univ., Knoxville, TN (United States). Dept. of Chemistry
Sponsoring Org:
DOE; USDOE, Washington, DC (United States)
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; 59 BASIC BIOLOGICAL SCIENCES; ELECTROPHORESIS; OPTIMIZATION; FULLERENES; LIQUID COLUMN CHROMATOGRAPHY; POLYCYCLIC AROMATIC HYDROCARBONS; ANTIBODIES; CAPILLARY FLOW; CHEMILUMINESCENCE; DERIVATIZATION; FLUORESCENCE SPECTROSCOPY; IMMUNOASSAY; LASER SPECTROSCOPY; MICELLAR SYSTEMS; OPTICAL FIBERS; PROGRESS REPORT; AROMATICS; BIOASSAY; CARBON; CHEMICAL REACTIONS; CHROMATOGRAPHY; DOCUMENT TYPES; ELEMENTS; EMISSION SPECTROSCOPY; FIBERS; FLUID FLOW; HYDROCARBONS; LUMINESCENCE; NONMETALS; ORGANIC COMPOUNDS; SEPARATION PROCESSES; SPECTROSCOPY 400105* -- Separation Procedures; 550200 -- Biochemistry