Gallium scans of the thorax in patients with acquired immune deficiency syndrome (AIDS): Description and utilization
The pattern of distribution of gallium uptake in the thorax was investigated in patients (pts) with AIDS. Eleven pts (ages 18-53), all active homosexual males suspected of having acute pulmonary infection were studied. Ga lung scans were performed at 24-48 and/or 72 hrs. post injection. The diagnosis of AIDS was based on appropriate clinical and laboratory findings. The Ga activity in the lung was graded from zero = background to 4+ which is > liver activity. Eight of eleven pts have positive Ga scan while seven of eleven pts had positive CXR. Six pts had both positive CXR and Ga scan. One pt had a positive Ga scan with negative CXR, and one with positive CXR and negative Ga scan. The positive Ga scans included 3 pts with 4+ diffuse uptake, two pts with 2+ diffuse uptake, two pts with 1+ diffuse uptake, and two with hilar node uptake. Three pts have focal increased uptake superimposed on diffuse uptake. Two pts with 4+ diffuse uptake had mild abnormality on their CXR. One pt with 4+ uptake in the initial scan shows decreased activity on follow-up with clinical improvement after therapy. Thus, all but two pts with positive Ga scans had diffuse lung uptake. These two patients alone had B cell immunoblastic sarcoma and oral candidiasis. The pattern of Ga lung uptake in pts with AIDS reveal that a majority of positive scans are diffuse (6/8) and the intensity may suggest more active disease than CXR (2 normal) and, thus, the study may be useful in detecting changes from atypical pulmonary infection in this population.
- Research Organization:
- LAC/USC Medical Center, Los Angeles, CA
- OSTI ID:
- 6933854
- Report Number(s):
- CONF-840619-; TRN: 87-008769
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 25:5; Conference: 31. annual meeting of the Society of Nuclear Medicine, Los Angeles, CA, USA, 5 Jun 1984
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
AIDS
DIAGNOSIS
CHEST
RADIOISOTOPE SCANNING
GALLIUM ISOTOPES
DIAGNOSTIC USES
UPTAKE
LUNGS
AGE DEPENDENCE
LIVER
MALES
PATIENTS
THERAPY
TRACER TECHNIQUES
BODY
BODY AREAS
COUNTING TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
GLANDS
HEMIC DISEASES
INFECTIOUS DISEASES
ISOTOPE APPLICATIONS
ISOTOPES
ORGANS
RESPIRATORY SYSTEM
USES
VIRAL DISEASES
550601* - Medicine- Unsealed Radionuclides in Diagnostics