Advantages of using aquatic animals for biomedical research on reproductive toxicology

Journal Article · Wed Apr 01 00:00:00 EST 1987 · Environ. Health Perspect.; (United States)

DOI:https://doi.org/10.1289/ehp.877169· OSTI ID:6786003

Mottet, N K; Landolt, M L

Major advantages of the use of aquatic animals, such as trout, English sole, or sea urchins, for studying the mechanisms of reproductive toxicology are discussed. The remarkable synchrony of differentiation of gametes in large quantities for detailed morphologic and biochemical measurements enables research not readily done on mammalian nonseasonal breeders. Structural differences such as the absence of a fibrous sheath in the more simple structure of fish and sea urchin sperm flagella facilitates comparative study of the mechanism of action of microtubules in flagella movement and the coupling of mitochondrial energy production to microtubules movement.

• Research Organization: Univ. of Washington, Seattle, WA (United States)
• OSTI ID: 6786003
• Journal Information: Environ. Health Perspect.; (United States), Vol. 71
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AQUATIC ORGANISMS
PHYSIOLOGY
REPRODUCTION
WATER POLLUTION
TOXICITY
MICROTUBULES
MITOCHONDRIA
PHARMACOLOGY
SCANNING ELECTRON MICROSCOPY
SEA URCHINS
SPERMATOGENESIS
SPERMATOZOA
TROUT
ANIMALS
CELL CONSTITUENTS
ECHINODERMS
ELECTRON MICROSCOPY
FISHES
GAMETES
GAMETOGENESIS
GERM CELLS
INVERTEBRATES
MICROSCOPY
ORGANOIDS
POLLUTION
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology