Pediatric uses of In-111 WBC imaging
To evaluate the diagnostic efficacy of In-111 WBC imaging in pediatrics the authors have examined the records of children seen in the laboratory. During the past 4 years they have performed 45 pediatric In-111 WBC studies, half within 1984 alone, in 40 children aged one month to 20 years. In children under one year old they have labelled WBC from 5-10 cc. of the child's blood. They have preferred to transfuse infants after withdrawal of the blood for labelling rather than label donor blood. In twelve children (30%) there was diagnostic localization of labelled WBCs. Five children had equivocal results while three had distinct but false positive localization. The confusing effect of skin lesions of chicken pox and of lymphadenopathy was apparent in six patients. Thirteen children had normal studies. Overall this study of utilization of In-111 WBC in pediatrics suggests best utilization in colitis and abdominal and pelvic infections and in osteomyelitis, especially in distinguishing osteomyelitis from bone infarcts in sickle cell disease. There appears to be lesser utility in patients with palpable adenopathy or superficial infection. Although In-111 WBC imaging may provide clear evidence for active pneumonitis in cases where a chest x-ray is equivocal, such as cytomegalovirus infection, vague localization in bases of lungs, mediastimum or heart is a relatively common finding without known clinical significance.
- Research Organization:
- St. Louis Univ. Medical School, St. Louis, MO
- OSTI ID:
- 6639640
- Report Number(s):
- CONF-850611-
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 26:5; Conference: 32. annual meeting of the Society of Nuclear Medicine, Houston, TX, USA, 2 Jun 1985
- Country of Publication:
- United States
- Language:
- English
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CHILDREN
DISEASES
INDIUM 111
DIAGNOSTIC USES
ABDOMEN
BIOLOGICAL LOCALIZATION
BLOOD
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
IMAGE PROCESSING
IMAGES
LABELLED COMPOUNDS
LYMPHATIC SYSTEM
LYMPHOCYTES
PEDIATRICS
PELVIS
SKELETON
AGE GROUPS
ANIMAL CELLS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD CELLS
BODY
BODY AREAS
BODY FLUIDS
CONNECTIVE TISSUE CELLS
DAYS LIVING RADIOISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
INDIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LEUKOCYTES
MATERIALS
MEDICINE
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PROCESSING
RADIOISOTOPES
SOMATIC CELLS
USES
550601* - Medicine- Unsealed Radionuclides in Diagnostics