Ewing's sarcoma of the vertebral column
- Washington Univ. School of Medicine, St. Louis, MO
Twenty-two patients with vertebral primaries were registered in the Intergroup Ewing's Sarcoma Study between 1973 and 1977. The radiation doses to the primary tumors ranged between 3800 and 6200 rad. All patients received intensive combination chemotherapy. After a followup ranging between 14 and 62 months, 14 patients remained disease-free. All patients with primary tumor of the cervical and dorsal spine remained disease-free. Of eight patients with lesions in the distal spine, (sacrococcygeal region) six developed recurrence, in three a local recurrence was observed despite doses of 6000 rad or higher. Doses of 5000 rad or less (in addition to combination chemotherapy as used in the Intergroup Ewing's Study) appear adequate in controlling the primary tumors of the proximal segments of the spinal column.
- OSTI ID:
- 6603411
- Journal Information:
- Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 7:1; Conference: 21. annual meeting of the American Society of Therapeutic Radiologists, New Orleans, LA, USA, 23 Oct 1979
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
SARCOMAS
DELAYED RADIATION EFFECTS
TUMOR CELLS
RADIOSENSITIVITY
VERTEBRAE
BIOLOGICAL RECOVERY
CHEMOTHERAPY
DOSE-RESPONSE RELATIONSHIPS
EXTERNAL IRRADIATION
LOCAL RADIATION EFFECTS
PATIENTS
RADIATION DOSES
RADIATION MONITORING
RADIOTHERAPY
SURVIVAL CURVES
ANIMAL CELLS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
DISEASES
DOSES
IRRADIATION
MEDICINE
MONITORING
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
RADIATION EFFECTS
RADIOLOGY
RECOVERY
SKELETON
THERAPY
550603* - Medicine- External Radiation in Therapy- (1980-)
560151 - Radiation Effects on Animals- Man