Changes in expression of murine alpha- and beta-globin genes during development

Conference · Tue Sep 30 00:00:00 EDT 1986

OSTI ID:6597519

Popp, R A; D'Surney, S J; Wawrzyniak, C J

Polyacrylamide gel isoelectric focusing was used to separate the multiple embryonic and adult hemoglobins in order to determine the relative amounts of the a1 and a/sup 2/ gene products in fetal mice of the Hba/sup c/ and Hba/sup g2/ haplotypes. In addition, centrifugal elutriation was used to separte the nucleated and non-nucleated red cells in order to determine the relative amounts of the b1/sup s2/ and b2/sup s/ gene products in each subpopulation of erythryocytes in fetal mice of the Hbb/sup s2/ haplotype. 22 refs., 2 figs.

• Research Organization: Oak Ridge National Lab., TN (USA); Tennessee Univ., Oak Ridge (USA). Graduate School of Biomedical Sciences
• DOE Contract Number: AC05-84OR21400
• OSTI ID: 6597519
• Report Number(s): CONF-8609276-1; ON: DE87008788
• Resource Relation: Conference: 5. hemoglobin switching conference, Airlie, VA, USA, 30 Sep 1986; Other Information: Portions of this document are illegible in microfiche products
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
GLOBULINS-ALPHA
GENE REGULATION
GLOBULINS-BETA
HEMOGLOBIN
ONTOGENESIS
BIOCHEMISTRY
CELL DIFFERENTIATION
ELECTROPHORESIS
MICE
ANIMALS
CARBOXYLIC ACIDS
CHEMISTRY
GLOBIN
GLOBULINS
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
MAMMALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PIGMENTS
PORPHYRINS
PROTEINS
RODENTS
VERTEBRATES
550200* - Biochemistry
550800 - Morphology