Activation of chemical promutagens by Selenastrum capricornutum in the plant cell/microbe coincubation assay
- Hope College, Holland, MI (USA)
The critical balance of organisms living in aquatic environments is influenced by the presence and relationship of plants to those environments. However, even though plants occupy a fundamental trophic level within aquatic ecosystems, few studies have focused upon the effect of xenobiotics on aquatic plants, and even fewer studies have dealt with xenobiotic metabolism by aquatic plants. It is well established that plants can metabolize chemicals into mutagens. The impact of these unique plant-activated chemical mutagens on ecosystems, food chains and, ultimately, human health is an important question that will require intensive and integrative investigation. The plant cell/microbe coincubation assay is particularly advantageous for use with unicellular algae. The conditions of this assay are such that chemical metabolism and subsequent mutagen detection can be followed in intact algal cells under simulated field conditions. The purpose of this research was to demonstrate that a unicellular algal species could be used effectively in the plant cell/microbe coincubation assay to activate model chemical mutagens.
- OSTI ID:
- 6521516
- Journal Information:
- Bulletin of Environmental Contamination and Toxicology; (USA), Vol. 44:5; ISSN 0007-4861
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
BENZOPYRENE
CHEMICAL ACTIVATION
MUTAGENESIS
BIOASSAY
POLYCYCLIC NITRO COMPOUNDS
ADRIATIC SEA
ALGAE
AQUATIC ECOSYSTEMS
BACTERIA
FRESH WATER
MUTAGEN SCREENING
PLANT CELLS
SALMONELLA TYPHIMURIUM
XENOBIOTICS
AROMATICS
CONDENSED AROMATICS
ECOSYSTEMS
HYDROCARBONS
HYDROGEN COMPOUNDS
MEDITERRANEAN SEA
MICROORGANISMS
NITRO COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
OXYGEN COMPOUNDS
PLANTS
SALMONELLA
SCREENING
SEAS
SURFACE WATERS
WATER
560300* - Chemicals Metabolism & Toxicology