Current treatment of Graves' disease

Journal Article · Wed Apr 01 00:00:00 EST 1987 · Surg. Clin. North Am.; (United States)

OSTI ID:6518820

Harada, T; Shimaoka, K; Mimura, T; Ito, K

In this review we have described the rationale for the appropriate treatment of patients with Graves' disease. Because the etiology of this disorder remains obscure, its management remains controversial. Since antithyroid drugs and radioiodine became readily available in the early 1950s, they have been widely used for the treatment of thyrotoxicosis, and the number of cases treated surgically has markedly decreased. However, almost four decades of experience have disclosed an unexpectedly high incidence of delayed hypothyroidism after radioiodine treatment and a low remission rate after antithyroid therapy. As a result, surgery is again being advocated as the treatment of choice. The three modalities of treatment have different advantages and disadvantages, and selection of treatment is of importance. In principle, we believe that for most patients a subtotal thyroidectomy should be performed after the patient has been rendered euthyroid by antithyroid drugs. We attempt to leave a thyroid remnant of 6 to 8 gm.36 references.

• Research Organization: Kawasaki Medical School, Kurashiki, Japan
• OSTI ID: 6518820
• Journal Information: Surg. Clin. North Am.; (United States), Vol. 2
• Country of Publication: United States
• Language: English

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