Modeling of an industrial alcohol fermentation and simulation of the plant by a process simulator
- LSGC-ENSIC, Nancy (France)
- LSGC-ENSAIA, Vandoeuvre (France)
- ENSIGC, Toulouse (France)
The aim of the present study was the development of a general simulation module for fermentation within the framework of existing chemical process simulators. This module has been applied to an industrial plant which produces ethanol from beet molasses and fresh beet juice by Saccharomyces cerevisiae. An unstructured mechanistic model has been developed with kinetic laws that are based on a chemically defined reaction scheme which satisfies stoichiometric constraints. This model can be applied to different culture conditions and takes into account secondary byproducts such as higher alcohols. These byproducts are of prime importance and need to be correctly estimated because a sequence of distillation columns follow the fermentor in the plant. Important measurement campaigns have been performed on the plant to validate the model. Plant operation has been successfully simulated using the same kinetic model for both continuous and fed-batch modes of production.
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 64502
- Journal Information:
- Biotechnology and Bioengineering, Vol. 46, Issue 3; Other Information: PBD: 5 May 1995
- Country of Publication:
- United States
- Language:
- English
Similar Records
Simulation of the continuous fermentation of manioc hydrolysate
Effects of oxygen and ethanol on recombinant yeast fermentation for hepatitis B virus surface antigen production: Modeling and simulation studies